Product Details

VALACYCLOVIR HCL 1GM

Manufacturer: CAMBER PHARMACE

MFG#: 31722-0705-90

NDC: 31722-0705-90

PID: 418628

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Additional Information

Product NameValacyclovir Hcl 1Gm
ApplicationAntiviral Agent
Generic Drug NameValacyclovir Hydrochloride
Mechanism of Action (MOA)Inhibits viral DNA synthesis by being converted to acyclovir, which inhibits viral DNA polymerase
Strength1g
TypeOral
Volume1 Tablet (1g per tablet)
Side EffectsHeadache, nausea, abdominal pain, dizziness
PrecautionsUse caution in patients with renal impairment
Drug InteractionsPotential interactions with other nephrotoxic drugs, probenecid
Pregnancy CategoryCategory B (generally considered safe during pregnancy)
Half-lifeApproximately 2.5 to 3 hours
Storage RequirementsStore at room temperature, away from moisture and heat
IndicationsHerpes simplex virus infections (genital herpes, cold sores), shingles (herpes zoster), cytomegalovirus (CMV)

Description

Valacyclovir HCl 1g is an antiviral medication used for the treatment of various viral infections, particularly those caused by herpes viruses. It is the prodrug of acyclovir, meaning that it is converted into acyclovir in the body after ingestion. Valacyclovir is primarily used to manage conditions such as herpes simplex virus (HSV) infections, including genital herpes, cold sores, and shingles (herpes zoster). It is also utilized in preventing cytomegalovirus (CMV) infection following organ transplants.

The drug works by inhibiting viral DNA synthesis. Valacyclovir, once converted to acyclovir, interferes with the viral DNA polymerase enzyme, preventing the virus from replicating and spreading within the host. This mechanism of action is effective in reducing the severity and duration of the infection, as well as decreasing the risk of transmission in patients with herpes simplex virus.

Valacyclovir is typically administered orally, with dosage adjusted based on the condition being treated. It is generally well-tolerated, although common side effects include headaches, nausea, and abdominal pain. More serious but rare side effects may include renal issues and neurological effects, particularly in patients with compromised renal function.

Frequently Asked Questions (FAQs)

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VALACYCLOVIR HCL 1GM is manufactured by CAMBER PHARMACE.

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