Additional Information

Description

Rocuronium 100mg/10ml multiple-dose vials (MDV) are pharmaceutical preparations primarily used as a neuromuscular blocking agent during surgical procedures. Designed for intravenous administration, these vials contain a sterile solution of rocuronium bromide, a non-depolarizing neuromuscular blocker that competitively binds to nicotinic acetylcholine receptors at the neuromuscular junction, thereby preventing acetylcholine from initiating muscle contraction.

The formulation's precise concentration of 100mg per 10ml ensures accurate dosing tailored to patient needs under medical supervision. This medication acts quickly, inducing paralysis within approximately one minute of administration, making it effective for facilitating endotracheal intubation and ensuring muscle relaxation during surgery.

Careful monitoring is essential during its use to manage the duration of action, which typically lasts for about 30 to 60 minutes. Clinicians adjust dosages based on factors such as the patient's weight, age, and the nature of the surgical procedure to achieve optimal muscle relaxation without undue prolongation. The multi-dose nature of the vials allows for flexibility in dosing while maintaining sterility and ensuring cost-effectiveness in clinical settings.

Clinicians must exercise caution, especially in patients with underlying neuromuscular disorders or compromised renal function, as these conditions may affect the metabolism and excretion of rocuronium. Adverse effects such as respiratory depression, allergic reactions, and prolonged paralysis require vigilant monitoring and prompt intervention to mitigate potential risks during and after administration.